RE.PUBLIC@POLIMI pubblicazioni di ricerca del Politecnico di Milano

SACCHETTI, ALESSANDRO
 Distribuzione geografica
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Continente #
NA - Nord America 5.307
EU - Europa 2.217
AS - Asia 481
AF - Africa 10
SA - Sud America 5
Continente sconosciuto - Info sul continente non disponibili 4
OC - Oceania 3
Totale 8.027
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Nazione #
US - Stati Uniti d'America 5.236
IT - Italia 789
AT - Austria 303
SE - Svezia 233
UA - Ucraina 178
VN - Vietnam 159
CN - Cina 137
DE - Germania 137
FI - Finlandia 117
IE - Irlanda 110
GB - Regno Unito 100
CA - Canada 70
ES - Italia 57
CH - Svizzera 53
FR - Francia 45
IN - India 40
JP - Giappone 35
NL - Olanda 35
JO - Giordania 22
BE - Belgio 20
SG - Singapore 20
HK - Hong Kong 18
KR - Corea 17
IR - Iran 16
SK - Slovacchia (Repubblica Slovacca) 9
RU - Federazione Russa 8
CI - Costa d'Avorio 7
ID - Indonesia 5
EU - Europa 4
LT - Lituania 4
PT - Portogallo 4
AU - Australia 3
BR - Brasile 3
MU - Mauritius 3
PK - Pakistan 3
RO - Romania 3
TW - Taiwan 3
BG - Bulgaria 2
NO - Norvegia 2
TR - Turchia 2
AL - Albania 1
AR - Argentina 1
BH - Bahrain 1
CL - Cile 1
DK - Danimarca 1
GR - Grecia 1
IL - Israele 1
LU - Lussemburgo 1
MC - Monaco 1
MD - Moldavia 1
MX - Messico 1
PH - Filippine 1
RS - Serbia 1
SA - Arabia Saudita 1
SI - Slovenia 1
Totale 8.027
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Città #
Fairfield 827
Woodbridge 560
Chandler 537
Ashburn 420
Houston 341
Seattle 340
Wilmington 338
Vienna 297
Cambridge 277
Ann Arbor 253
Milan 126
Medford 110
Jacksonville 106
Lawrence 103
Dublin 93
Dearborn 87
Dong Ket 78
Beijing 72
Ottawa 68
Málaga 56
San Diego 55
Helsinki 51
Bern 41
Des Moines 29
New York 29
Amsterdam 28
Redwood City 28
Amman 22
London 20
Redmond 20
Brussels 19
Miami 19
Rome 19
Columbus 18
Norwalk 14
Torino 12
Shanghai 11
Turin 11
Hong Kong 10
Menlo Park 10
San Giuliano Milanese 10
Florence 9
Fremont 9
Bratislava 8
Duncan 8
Santa Giustina 8
Abidjan 7
Los Angeles 7
Pavia 7
Seongnam 7
Washington 7
Châtenay-malabry 6
Civitanova Marche 6
Santorso 6
Stockholm 6
Torre Boldone 6
Auburn Hills 5
Guangzhou 5
Isola Della Scala 5
Manchester 5
Monza 5
Pordenone 5
Singapore 5
Vallda 5
Barzanò 4
Casale Monferrato 4
Hounslow 4
Islington 4
Jakarta 4
Kilburn 4
Kumar 4
Kunming 4
Moscow 4
Nyon 4
Portland 4
Tokyo 4
Trieste 4
Urbino 4
Vilnius 4
Zurich 4
Alessandria 3
Bocale 3
Campomorone 3
Castelleone 3
Chengdu 3
Como 3
Edinburgh 3
Fort Worth 3
Karlsruhe 3
L'aquila 3
Lanzhou 3
Leawood 3
Legnano 3
Lugano 3
Parma 3
Phoenix 3
Salvador 3
Serina 3
Shenyang 3
Siena 3
Totale 5.836
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Nome #
Design of Multifunctional Polysaccharides for Biomedical Applications: A Critical Review 158
Plasmonic control of drug release efficiency in agarose gel loaded with gold nanoparticle assemblies 143
Cascade Coupling of Ene Reductases with Alcohol Dehydrogenases: Enantioselective Reduction of Prochiral Unsaturated Aldehydes 124
Chemoselective functionalization of nanogels for microglia treatment 122
Asymmetric Ugi 3CR on isatin-derived ketimine: Synthesis of chiral 3,3-disubstituted 3-aminooxindole derivatives 118
Highly Dynamic and Tunable Behavior of 1D Coordination Polymers Based on the Bispidine Ligand 115
Addition of TMSCN to chiral ketimines derived from isatin. Synthesis of an oxindole-based peptidomimetic and a bioactive spirohydantoin 111
Microwave-assisted synthesis of TEMPO-labeled hydrogels traceable with MRI 108
Preparation and Luminescence Thermochromism of Tetranuclear Copper(I)–Pyridine–Iodide Clusters 107
Deep Eutectic Solvents: Promising Media for advanced hydrometallurgical processes for actinides separation 103
Chiral diamines for asymmetric synthesis: an efficient RCM construction of the ligand core of (-)- and (+)-sparteine 102
Double conjugated nanogels for selective intracellular drug delivery 102
3D integration of pH-cleavable drug-hydrogel conjugates on magnetically driven smart microtransporters 102
A chemoenzymatic-RCM strategy for the enantioselective synthesis of new dihydroxylated 5-hydroxymethyl-indolizidines and 6-hydroxymethyl-quinolizidines 101
Biphasic porous structures formed by monomer/water interface stabilization with colloidal nanoparticles 99
Deep Eutectic Solvents: Un’innovativa classe di estraenti per il processo di separazione di attinidi. 98
Evaluation of RGD functionalization in hybrid hydrogels as 3D neural stem cell culture systems 96
Application of chiral bi- and tetra-dentate bispidine-derived ligands in the copper(ii)-catalyzed asymmetric Henry reaction 96
Thiocolchicine-podophyllotoxin conjugates: Dynamic libraries based on disulfide exchange reaction 95
Structural properties of the chelating agent 2,6-bis(1-(3-hydroxypropyl)-1,2,3-triazol-4-yl)pyridine: a combined XRD and DFT structural study 94
On the structure and spectroscopic properties of sparteine and its diastereoisomers 93
Comparison between two different click strategies to synthesize fluorescent nanogels for therapeutic applications 93
A new spirocyclic proline-based lactam as efficient type II' b-turn inducing peptidomimetic 92
Biocatalysed olefin reduction of 3-alkylidene oxindoles by baker's yeast 92
Structural and Biological Exploration of Phe3–Phe4-Modified Endomorphin-2 Peptidomimetics 91
Concise asymmetric synthesis of (-)-halosaline and (2R,9aR)-(+)-2-hydroxy-quinolizidine by ruthenium-catalyzed ring-rearrangement metathesis 90
Asymmetric Synthesis of Molecules Containing the Bispidine Core 90
Design, synthesis, and conformational analysis of 3-: Cyclo -butylcarbamoyl hydantoins as novel hydrogen bond driven universal peptidomimetics 88
Biotechnological Development of a Practical Synthesis of Ethyl (S)-2-Ethoxy-3-(p-methoxyphenyl)propanoate (EEHP): Over 100-Fold Productivity Increase from Yeast Whole Cells to Recombinant Isolated Enzymes 87
Effect of chirality and lipophilicity in the functional activity of evodiamine and its analogues at TRPV1 channels 86
Chiral amino-amides as solution phase and immobilized ligands for the catalytic asymmetric alkylation of aromatic aldehydes 85
Substrate-engineering approach to the stereoselective chemo-multienzymatic cascade synthesis of Nicotiana tabacum lactone 85
Deep eutectic solvent as solvent and catalyst: One-pot synthesis of 1,3-dinitropropanes via tandem Henry reaction/Michael addition 85
A new three dimensional biomimetic hydrogel to deliver factors secreted by human mesenchymal stem cells in spinal cord injury 85
Inhibitors of tubulin polymerization: Synthesis and biological evaluation of hybrids of vindoline, anhydrovinblastine and vinorelbine with thiocolchicine, podophyllotoxin and baccatin III. 84
Synthesis and conformational analysis of benzimidazole-based reverse turn mimics 83
New chiral diamino ligands as sparteine analogues. Application to the palladium-catalyzed kinetic oxidative resolution of 1-phenyl ethanol 82
Grignard Addition to Imines Derived from Isatine: A Method for the Asymmetric Synthesis of Quaternary 3-Aminooxindoles. 82
Modulation of electrostatic interactions to improve controlled drug delivery from nanogels 82
Complementary isonitrile-based multicomponent reactions for the synthesis of diversified cytotoxic hemiasterlin analogues 82
Influence of the Core Formulation on Features and Drug Delivery Ability of Carbamate-Based Nanogels 81
Deep Eutectic Solvents: Promising Co-solvents to Improve the Extraction Kinetics of CyMe4-BTBP 81
Tunable drug delivery using chemoselective functionalization of hydrogels 79
Synthesis of 3-Heteroaryloxindoles through t-BuOCl-Mediated Oxidation of 3-Heteroarylindoles 78
Productivity enhancement of C=C bioreductions by coupling the in situ substrate feeding product removal technology with isolated enzymes. 78
Olefin Metathesis Based Approach to Diversely Functionalized Pyrrolizidines and Indolizidines; Total Synthesis of (+)-Monomorine 77
The diketopiperazine-fused tetrahydro-β-carboline scaffold as a model peptidomimetic with an unusual α-turn secondary structure 77
Hydrogel supported chiral imidazolidinone for organocatalytic enantioselective reduction of olefins in water 77
Rapid access to reverse-turn peptidomimetics by a three-component Ugi reaction of 3,4-dihydroisoquinoline 77
Design of polymer-based antimicrobial hydrogels through physico-chemical transition 76
Synthesis of Robalzotan, Ebalzotan, and Rotigotine Precursors via the Stereoselective Multienzymatic Cascade Reduction of α,β-Unsaturated Aldehydes 76
Biocatalytic enantioselective approach to 3-aryl-2-nitropropanols: Synthesis of enantioenriched (R)-5-methoxy-3-aminochroman, a key precursor to the antidepressant drug Robalzotan 76
Multicomponent Approach to Libraries of Substituted Dihydroorotic Acid Amides 75
Synthesis, pharmacological evaluation and conformational investigation of endomorphin-2 hybrid analogues 75
Palladium-catalyzed hydroxycarbonylation of aryl and vinyl triflates by in situ generated carbon monoxide under microwave irradiation 74
Synthesis of tetrahydroisoquinoline-based pseudopeptides and their characterization as suitable reverse turn mimetics 71
Hemiasterlin analogues incorporating an aromatic, and heterocyclic type C-terminus: design, synthesis and biological evaluation 71
Short enantioselective synthesis of sedridines, ethylnorlobelols and coniine via reagent-based differentiation 69
Quinazolinecarboline alkaloid evodiamine as scaffold for targeting topoisomerase I and sirtuins 69
Substrate scope and synthetic applications of the enantioselective reduction of α-alkyl-β-arylenones mediated by Old Yellow Enzymes 69
Pyrroloisoquinoline-based tetrapeptide analogues mimicking reverse-turn secondary structures 69
Effects of primary amine-based coatings on microglia internalization of nanogels 69
Enantioselective copper-catalyzed cyclopropanation of styrene by means of chiral bispidine ligands 68
Synthesis of RGD-functionalized hydrogels as a tool for therapeutic applications 67
Synthesis of Enantiopure Diamine Ligands Related to Sparteine, via Scandium Triflate Catalyzed Imino Diels-Alder Reactions 66
Stereocontrolled reduction of an oxazepinohexahydroindolo[2,3-a]quinolizine derivative: asymmetric total synthesis of (+)-tacamonine 66
Tetrahydro-β-carboline-Based Spirocyclic Lactam as Type II′ β-Turn: Application to the Synthesis and Biological Evaluation of Somatostatine Mimetics 66
Simple and efficient strategy to synthesize PEG-aldehyde derivatives for hydrazone orthogonal chemistry 66
An efficient enantioselective approach to cyclic beta-amino acid derivatives via olefin metathesis reactions 65
Spectroscopic, Structural, and Computational Characterization of Three Bispidinone Derivatives, as Ligands for Enantioselective Metal Catalyzed Reactions 63
Functionalized Nanogel for Treating Activated Astrocytes in Spinal Cord Injury 62
Total enantioselective synthesis of (-)-cytisine 61
Co-Polymeric Nanosponges from Cellulose Biomass as Heterogeneous Catalysts for amine-catalyzed Organic Reactions 61
Organocatalytic vinylogous Mannich reaction of trimethylsiloxyfuran with isatin-derived benzhydryl-ketimines 61
null 60
Sistema composito comprendente idrogelo e nano-particella/e per il contenimento, la veicolazione e il rilascio multiplo di farmaco/i e cellula/e 60
Combinatorial solid-phase synthesis of 6-hydroxy-1,2,3,4-tetrahydro-beta-carbolines from L-5-hydroxytryptophan 59
Combined structural and theoretical investigation on differently substituted bispidine ligands: predicting the properties of their corresponding coordination polymers 59
Total synthesis of 275A lehmizidine frog skin alkaloid (or of its enantiomer) 57
Organocatalytic Asymmetric Biginelli-like Reaction Involving Isatin 57
Stereoselectivity switch in the reduction of α-Alkyl-β-arylenones by structure-guided designed variants of the ene reductase OYE1 56
New solution free and polymer anchored chiral bispidine-based amino alcohols. Synthesis and screening for the enantioselectiveaddition of diethylzinc to benzaldehyde 55
Ugi 4-CR/Pictet–Spengler reaction as a short route to tryptophan-derived peptidomimetics 55
Synthesis and Antimicrobial Evaluation of Novel Chiral 2-Amino-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Derivatives 55
Critical survey covering the year 2010: total synthesis of natural products 54
PRODOTTO DA FUMO O DA AEROSOL 53
The spiropiperidine-3,3 '-oxindole scaffold: a type II beta-turn peptide isostere 53
Ester coupling of ibuprofen in hydrogel matrix: A facile one-step strategy for controlled anti-inflammatory drug release 53
Synthesis and characterization of a “clickable” PBR28 TSPO-selective ligand derivative suitable for the functionalization of biodegradable polymer nanoparticles 53
Selective Modulation of A1 Astrocytes by Drug-Loaded Nano-Structured Gel In Spinal Cord Injury 50
Lipase-Catalyzed Kinetic Resolution of Alcohols as Intermediates for the Synthesis of Heart Rate Reducing Agent Ivabradine 50
Is nanoparticle functionalization a versatile approach to meet challenges of drug and gene delivery? 48
Multi-enzymatic stereoselective synthesis of chiral synthons and pharmaceutical intermediates 44
trans-6- Amino-cyclohept-3-enols, a new designed polyfunctionalized chiral building block for the asymmetric synthesis of 2-subtituted-4-hydroxy piperidines 43
Phe-Ala-Based Diazaspirocyclic Lactam as Nucleator of Type II ' beta-Turn 42
New Tetracyclic Colchicinoids from Reaction of N- Deacetylthiocolchicine and N-Deacetylcolchicine with Nitrous Acid and t-Butyl Nitrite 41
Productivity Improvement of the Bioreduction of α,β-Unsaturated Aldehydes by Coupling of the In Situ Substrate Feeding Product Removal (SFPR) Strategy with Isolated Enzymes 41
Effect of surface decoration on properties and drug release ability of nanogels 41
A perspective on the applications of functionalized nanogels: promises and challenges 39
Pd-Loaded Cellulose NanoSponge as a Heterogeneous Catalyst for Suzuki–Miyaura Coupling Reactions 38
Totale 7.663
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Categoria #
all - tutte 26.204
article - articoli 24.637
book - libri 0
conference - conferenze 691
curatela - curatele 0
other - altro 0
patent - brevetti 308
selected - selezionate 0
volume - volumi 568
Totale 52.408
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019646 0 0 0 0 0 0 0 0 0 139 259 248
2019/20201.805 104 103 43 129 210 214 213 171 216 117 210 75
2020/20211.371 101 70 119 91 123 60 132 131 119 119 87 219
2021/20221.088 29 123 66 160 119 39 51 77 79 66 108 171
2022/20231.480 145 114 58 147 180 215 14 118 226 84 98 81
2023/2024618 72 121 69 91 59 106 21 64 9 6 0 0
Totale 8.155