The Henry reaction was performed using microwave heating within the deep eutectic solvent (DES) choline chloride/urea (ChCl/urea) which acted as both the catalyst and solvent for the reaction. The optimisation of the conditions (temperature, heating mode, time, DES) allowed 1,3-dinitropropane derivatives to be obtained via tandem Henry reaction/Michael addition, in one step from a range of different aromatic aldehydes in high yields and under mild reaction conditions

Deep eutectic solvent as solvent and catalyst: One-pot synthesis of 1,3-dinitropropanes via tandem Henry reaction/Michael addition

G. Colombo Dugoni;A. Sacchetti;A. Mele
2020

Abstract

The Henry reaction was performed using microwave heating within the deep eutectic solvent (DES) choline chloride/urea (ChCl/urea) which acted as both the catalyst and solvent for the reaction. The optimisation of the conditions (temperature, heating mode, time, DES) allowed 1,3-dinitropropane derivatives to be obtained via tandem Henry reaction/Michael addition, in one step from a range of different aromatic aldehydes in high yields and under mild reaction conditions
deep eutectic solvents, Henry reaction, Michael reaction, microwaves
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11311/1149704
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