The emerging treatments for Tricuspid Valve (TV) pathologies leads to the need for realistic pathological models of TV, aimed at studying these new approaches. The most common TV pathology is Functional Tricuspid Regurgitation (FTR) where annulus and right ventricle dilation leads to valve incontinence. Defrosted porcine hearts were used in pulsatile mock loops as an experimental model of FTR, but a systematic characterization of the experimental model is lacking. In this work we compared the TV geometrical morphology in fresh and defrosted porcine hearts to assess the porcine heart as an ex-vivo model of FTR.
CHARACTERIZATION OF AN EX-VIVO PORCINE MODEL OF FUNCTIONAL TRICUSPID REGURGITATION
E. Salurso;M. Jaworek;F. Perico;G. Gelpi;G. B. Fiore;R. Vismara
2021-01-01
Abstract
The emerging treatments for Tricuspid Valve (TV) pathologies leads to the need for realistic pathological models of TV, aimed at studying these new approaches. The most common TV pathology is Functional Tricuspid Regurgitation (FTR) where annulus and right ventricle dilation leads to valve incontinence. Defrosted porcine hearts were used in pulsatile mock loops as an experimental model of FTR, but a systematic characterization of the experimental model is lacking. In this work we compared the TV geometrical morphology in fresh and defrosted porcine hearts to assess the porcine heart as an ex-vivo model of FTR.File in questo prodotto:
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