In this paper, a time-domain fast gated near-infrared spectroscopy system is presented. The system is composed of a fiber-based laser providing two pulsed sources and two fast gated detectors. The system is characterized on phantoms and was tested in vivo, showing how the gating approach can improve the contrast and contrast-to-noise-ratio for detection of absorption perturbation inside a diffusive medium, regardless of source-detector separation.

A Versatile Setup for Time-Resolved Functional Near Infrared Spectroscopy Based on Fast-Gated Single-Photon Avalanche Diode and on Four-Wave Mixing Laser

Laura Di Sieno;Alberto Dalla Mora;Alessandro Torricelli;Lorenzo Spinelli;Rebecca Re;Antonio Pifferi;Davide Contini
2019-01-01

Abstract

In this paper, a time-domain fast gated near-infrared spectroscopy system is presented. The system is composed of a fiber-based laser providing two pulsed sources and two fast gated detectors. The system is characterized on phantoms and was tested in vivo, showing how the gating approach can improve the contrast and contrast-to-noise-ratio for detection of absorption perturbation inside a diffusive medium, regardless of source-detector separation.
time-domain NIRS; null source-detector separation; brain; diffuse optics
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11311/1124033
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