A bone tissue phantom prototype allowing to test, in general, optical flowmeters at large interoptode spacings, such as laser-Doppler flowmetry or diffuse correlation spectroscopy, has been developed by 3D-stereolithography technique. It has been demonstrated that complex tissue vascular systems of any geometrical shape can be conceived. Absorption coefficient, reduced scattering coefficient and refractive index of the optical phantom have been measured to ensure that the optical parameters reasonably reproduce real human bone tissue in vivo. An experimental demonstration of a possible use of the optical phantom, utilizing a laser-Doppler flowmeter, is also presented.

Bone tissue phantoms for optical flowmeters at large interoptode spacing generated by 3D-stereolithography

TORRICELLI, ALESSANDRO;SPINELLI, LORENZO
2014-01-01

Abstract

A bone tissue phantom prototype allowing to test, in general, optical flowmeters at large interoptode spacings, such as laser-Doppler flowmetry or diffuse correlation spectroscopy, has been developed by 3D-stereolithography technique. It has been demonstrated that complex tissue vascular systems of any geometrical shape can be conceived. Absorption coefficient, reduced scattering coefficient and refractive index of the optical phantom have been measured to ensure that the optical parameters reasonably reproduce real human bone tissue in vivo. An experimental demonstration of a possible use of the optical phantom, utilizing a laser-Doppler flowmeter, is also presented.
Medical optics and biotechnology; Medical optics instrumentation; Laser Doppler velocimetry; Blood or tissue constituent monitoring; Flow diagnostics
File in questo prodotto:
File Dimensione Formato  
Binzoni_BOE_5_2715_full_text_PUBBLICO.pdf

Accesso riservato

: Publisher’s version
Dimensione 1.11 MB
Formato Adobe PDF
1.11 MB Adobe PDF   Visualizza/Apri
Manoscritto_inviato_a_BOE_PhantomLDF2.pdf

accesso aperto

: Pre-Print (o Pre-Refereeing)
Dimensione 609.69 kB
Formato Adobe PDF
609.69 kB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11311/952757
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 5
  • ???jsp.display-item.citation.isi??? 4
social impact