We have designed a compact dual wavelength (687 nm, 826 nm) multi-channel (16 sources, 8 detectors) medical device for muscle and brain imaging based on time domain functional near infrared spectroscopy. The system employs the wavelength space multiplexing approach to reduce wavelength cross-talk and increase signal-to-noise ratio. System performances have been tested on homogeneous and heterogeneous tissue phantoms following specifically designed protocols for photon migration instruments. Preliminary in vivo measurements have been performed to validate the instrument capability to monitor hemodynamic parameters changes in the arm muscle during arterial occlusion and in the adult head during a motor task experiment.

Multi-channel medical device for time domain functional near infrared spectroscopy based on wavelength space multiplexing

RE, REBECCA;CONTINI, DAVIDE;SPINELLI, LORENZO;ZUCCHELLI, LUCIA MARIA GRAZIA;CAFFINI, MATTEO;CUBEDDU, RINALDO;TORRICELLI, ALESSANDRO
2013

Abstract

We have designed a compact dual wavelength (687 nm, 826 nm) multi-channel (16 sources, 8 detectors) medical device for muscle and brain imaging based on time domain functional near infrared spectroscopy. The system employs the wavelength space multiplexing approach to reduce wavelength cross-talk and increase signal-to-noise ratio. System performances have been tested on homogeneous and heterogeneous tissue phantoms following specifically designed protocols for photon migration instruments. Preliminary in vivo measurements have been performed to validate the instrument capability to monitor hemodynamic parameters changes in the arm muscle during arterial occlusion and in the adult head during a motor task experiment.
Photon migration; Medical optics instrumentation; Time-resolved imaging; Blood or tissue constituent monitoring; Clinical applications; Functional monitoring and imaging
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11311/754840
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