M r = 241.26, monoclinic, P21/c, a = 12.609 (6), b= 7.681 (4), c= 12.645 (6)A, /3= 94.97 (2) °, U= 1220.05 A 3, z=4, Dx= 1.31 gcm -3, 2(Mo K~) = 0.71069 A, /~ = 0.619 cm -~, F(000) = 476, room temperature, R = 0.064 for 1232 observed reflections. The product, a new synthetic molecule showing some activity as an inhibitor of the biosynthesis of ergosterol in fungi, shows a quaternary central C and the presence of two aromatic rings, one containing N (pyridine). These rings are inclined at an angle of 84 (1.1) ° to each other.
STRUCTURE OF ERGOSTEROLBIOSYNTHESIS INHIBITORS .1. STRUCTURE OF 1-(4-FLUOROPHENYL)-1-(3-PYRIDYL)-BUT-3-YN-1-OL, C15H12FNO
MEILLE, STEFANO VALDO;
1985-01-01
Abstract
M r = 241.26, monoclinic, P21/c, a = 12.609 (6), b= 7.681 (4), c= 12.645 (6)A, /3= 94.97 (2) °, U= 1220.05 A 3, z=4, Dx= 1.31 gcm -3, 2(Mo K~) = 0.71069 A, /~ = 0.619 cm -~, F(000) = 476, room temperature, R = 0.064 for 1232 observed reflections. The product, a new synthetic molecule showing some activity as an inhibitor of the biosynthesis of ergosterol in fungi, shows a quaternary central C and the presence of two aromatic rings, one containing N (pyridine). These rings are inclined at an angle of 84 (1.1) ° to each other.File in questo prodotto:
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