The relative stereochemistry of the four stereocentres of spirolaxine 1, a bioactive 6,5-spiroacetal phthalide secondary metabolite, was determined through single-crystal X-ray analysis. Its absolute configuration was determined by circular dichroism; the experimental spectrum of spirolaxine is in good agreement with that evaluated by means of DeVoe coupled-oscillator calculations.
Absolute Configuration of the Fungal Metabolite Spirolaxine
MALPEZZI, LUCIANA;MEILLE, STEFANO VALDO;
2005-01-01
Abstract
The relative stereochemistry of the four stereocentres of spirolaxine 1, a bioactive 6,5-spiroacetal phthalide secondary metabolite, was determined through single-crystal X-ray analysis. Its absolute configuration was determined by circular dichroism; the experimental spectrum of spirolaxine is in good agreement with that evaluated by means of DeVoe coupled-oscillator calculations.File in questo prodotto:
| File | Dimensione | Formato | |
|---|---|---|---|
|
Bava Meille Malpezzi 2005.pdf
Accesso riservato
:
Altro materiale allegato
Dimensione
137.74 kB
Formato
Adobe PDF
|
137.74 kB | Adobe PDF | Visualizza/Apri |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
