Survival analysis is an essential tool in healthcare for risk assessment, assisting clinicians in their evaluation and decision making processes. Therefore, the importance of using expressive and high-performing survival models is crucial. With the advent of neural networks and deep learning, a new generation of survival models has emerged, offering state-of-the-art capabilities to capture the non-linear and complex relationships inherent in multimodal patient data for survival prediction. However, these models often produce discrete outputs, resulting in survival functions that are coarse-grained and difficult to interpret. This study advances previous research by further exploring interpolation techniques as a post-processing strategy to improve the predictive accuracy of survival models. Our results show how the use of specific interpolation techniques significantly improves the concordance and calibration of survival estimates. This analysis encompasses a wide array of medical datasets, models, and interpolation techniques, demonstrating the effectiveness of the proposed approach and providing actionable insights for survival model design.

Bridging the gap: improve neural survival models with interpolation techniques

Archetti, Alberto;Matteucci, Matteo
2024-01-01

Abstract

Survival analysis is an essential tool in healthcare for risk assessment, assisting clinicians in their evaluation and decision making processes. Therefore, the importance of using expressive and high-performing survival models is crucial. With the advent of neural networks and deep learning, a new generation of survival models has emerged, offering state-of-the-art capabilities to capture the non-linear and complex relationships inherent in multimodal patient data for survival prediction. However, these models often produce discrete outputs, resulting in survival functions that are coarse-grained and difficult to interpret. This study advances previous research by further exploring interpolation techniques as a post-processing strategy to improve the predictive accuracy of survival models. Our results show how the use of specific interpolation techniques significantly improves the concordance and calibration of survival estimates. This analysis encompasses a wide array of medical datasets, models, and interpolation techniques, demonstrating the effectiveness of the proposed approach and providing actionable insights for survival model design.
2024
Progress in Artificial Intelligence
9780853128304
Healthcare
Interpolation techniques
Machine learning
Neural networks
Survival analysis
File in questo prodotto:
File Dimensione Formato  
s13748-024-00343-y.pdf

Accesso riservato

: Publisher’s version
Dimensione 7.45 MB
Formato Adobe PDF
7.45 MB Adobe PDF   Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11311/1312352
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 1
  • ???jsp.display-item.citation.isi??? 0
social impact