Performance and reproducibility assessment across multiple time-domain near-infrared spectroscopy device replicas

Reproducibility between different replicas of the same device is an important aspect in the biomedical research field. Multiple replicas of a dual-wavelength, single-channel “NIRSBOX” device have been assembled and characterized. In this work, we present their full performance assessment. Characterization is focused on measurement accuracy, reproducibility, and reliability, following well-defined and widely adopted procedures to assess the quality of diffuse-optics instruments. The results of the performance assessment procedures are promising, demonstrating highly reproducible performances over different time-domain near-infrared spectroscopy devices, a feature of paramount importance when it comes to comparing results from different instruments, e.g. in multicenter studies.