In this work, we investigate a distributed optimal control problem for an extended phase field system of Cahn–Hilliard type which physical context is that of tumor growth dynamics. In a previous contribution, the author has already studied the corresponding problem for the logarithmic potential. Here, we try to extend the analysis by taking into account a non-smooth singular nonlinearity, namely the double obstacle potential. Due to its non-smoothness behavior, the standard procedure to characterize the necessary conditions for the optimality cannot be performed. Therefore, we follow a different strategy which in the literature is known as the “deep quench” approach in order to obtain some optimality conditions that have to be interpreted in a more general framework. We establish the existence of optimal controls and some first-order optimality conditions for the system are derived by employing suitable approximation schemes.

Optimality conditions for an extended tumor growth model with double obstacle potential via deep quench approach

Signori A.
2020-01-01

Abstract

In this work, we investigate a distributed optimal control problem for an extended phase field system of Cahn–Hilliard type which physical context is that of tumor growth dynamics. In a previous contribution, the author has already studied the corresponding problem for the logarithmic potential. Here, we try to extend the analysis by taking into account a non-smooth singular nonlinearity, namely the double obstacle potential. Due to its non-smoothness behavior, the standard procedure to characterize the necessary conditions for the optimality cannot be performed. Therefore, we follow a different strategy which in the literature is known as the “deep quench” approach in order to obtain some optimality conditions that have to be interpreted in a more general framework. We establish the existence of optimal controls and some first-order optimality conditions for the system are derived by employing suitable approximation schemes.
2020
Adjoint system
Asymptotic analyses
Cahn
Deep quench
Distributed optimal control
Hilliard equation
Necessary optimality conditions
Optimal control
Phase field model
Tumor growth
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11311/1218887
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