Hydrogels are highly hydrated three dimensional polymeric cross-linked networks that excel over other biomaterials to nearly mimic the native tissue microenvironment. However, limited mechanical stiffness and failure after cyclic loading significantly hinder their biomedical applications1. Despite recent progress in preparing stiff and tough hydrogels, it’s still challenging to design a cell-compatible, Objective highly porous and high modulus hydrogels in a congenial and sustainable approach. Developing a novel nanobiocomposite network hydrogels in combination of graphene nanoplatelet and gelatin/chitosan polymer matrix maintaining more mechanical modulus, stability and strength without sacrificing pore morphology and internal hydrogel architecture utilizing a simple, green andenvironment-friendly fabrication approach.
Novel Nanobiocomposite Hydrogels Based on Gelatin/Chitosan and Functionalized Graphene
Lopomo N.;Barbera V.;Galimberti M.
2018-01-01
Abstract
Hydrogels are highly hydrated three dimensional polymeric cross-linked networks that excel over other biomaterials to nearly mimic the native tissue microenvironment. However, limited mechanical stiffness and failure after cyclic loading significantly hinder their biomedical applications1. Despite recent progress in preparing stiff and tough hydrogels, it’s still challenging to design a cell-compatible, Objective highly porous and high modulus hydrogels in a congenial and sustainable approach. Developing a novel nanobiocomposite network hydrogels in combination of graphene nanoplatelet and gelatin/chitosan polymer matrix maintaining more mechanical modulus, stability and strength without sacrificing pore morphology and internal hydrogel architecture utilizing a simple, green andenvironment-friendly fabrication approach.File | Dimensione | Formato | |
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