In order to study hemodynamic changes involved in muscular metabolism by means of time domain fNIRS, we need to discriminate in the measured signal contributions coming from different depths. Muscles are, in fact, typically located under other tissues, e.g. skin and fat. In this paper, we study the possibility to exploit a previously proposed method for analyzing time-resolved fNIRS measurements in a two-layer structure with a thin superficial layer. This method is based on the calculation of the timedependent mean partial pathlengths. We validated it by simulating venous and arterial arm cuff occlusions and then applied it on in vivo measurements.

Effect of a thin superficial layer on the estimate of hemodynamic changes in a two-layer medium by time domain NIRS

RE, REBECCA;CONTINI, DAVIDE;ZUCCHELLI, LUCIA MARIA GRAZIA;TORRICELLI, ALESSANDRO;SPINELLI, LORENZO
2016-01-01

Abstract

In order to study hemodynamic changes involved in muscular metabolism by means of time domain fNIRS, we need to discriminate in the measured signal contributions coming from different depths. Muscles are, in fact, typically located under other tissues, e.g. skin and fat. In this paper, we study the possibility to exploit a previously proposed method for analyzing time-resolved fNIRS measurements in a two-layer structure with a thin superficial layer. This method is based on the calculation of the timedependent mean partial pathlengths. We validated it by simulating venous and arterial arm cuff occlusions and then applied it on in vivo measurements.
Photon migration; Blood or tissue constituent monitoring; Functional monitoring and imaging; Time-resolved imaging
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11311/1015410
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