This work presents a CFD approach for modeling the blood flow in a hollow-fiber membrane oxygenator with an integrated heat exchanger. Platelet-like particles were modeled with a Discrete Phase Modeling approach to identify their trajectories and shear stress history. Simulations were run on ANSYS Fluent and coupled with experimental tests on human platelets in order to evaluate the thrombogenic potential of the device during extracorporeal circulation.
CFD-guided evaluation of platelet activation in medical devices: a case study with blood oxygenators
PELOSI, ALESSANDRA;STEVANELLA, MARCO;FIORE, GIANFRANCO BENIAMINO;REDAELLI, ALBERTO CESARE LUIGI
2012-01-01
Abstract
This work presents a CFD approach for modeling the blood flow in a hollow-fiber membrane oxygenator with an integrated heat exchanger. Platelet-like particles were modeled with a Discrete Phase Modeling approach to identify their trajectories and shear stress history. Simulations were run on ANSYS Fluent and coupled with experimental tests on human platelets in order to evaluate the thrombogenic potential of the device during extracorporeal circulation.File in questo prodotto:
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