This work describes a convenient, fast and low cost method of embedding a high-conductive and flexible material within microfluidic devices as a means to realize uniform electric fields within 3D cellular microenvironments. Fluidic channels and electrodes are fabricated by traditional soft-lithography in conjunction with chemical etching of PDMS. Devices can be deformable (thus allowing for a combination of electro-mechanical stimulation), they are made from inexpensive materials and easily assembled by hand; this method is thus accessible to a wide range of laboratories and budgets.

3D flexible electrodes in microfluidic devices for cell culture stimulations

RASPONI, MARCO;PIRAINO, FRANCESCO;REDAELLI, ALBERTO CESARE LUIGI;FIORE, GIANFRANCO BENIAMINO
2012-01-01

Abstract

This work describes a convenient, fast and low cost method of embedding a high-conductive and flexible material within microfluidic devices as a means to realize uniform electric fields within 3D cellular microenvironments. Fluidic channels and electrodes are fabricated by traditional soft-lithography in conjunction with chemical etching of PDMS. Devices can be deformable (thus allowing for a combination of electro-mechanical stimulation), they are made from inexpensive materials and easily assembled by hand; this method is thus accessible to a wide range of laboratories and budgets.
Congresso Nazionale di Bioingegneria 2012 Atti
9788855531825
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11311/665732
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