The reduction of (Z)-3-fluoro-4-phenyl-1-(p-tolylsulphonyl)but-3-en-2-one with growing cultures of Geotrichum candidum and Phanerochaete chrysosporium afforded (S)- and (R)-3-fluoro-4-phenyl-1-(p-tolylsulphonyl)but-3-en-2-ol in enantiomerically pure form.
Homochiral fluoro-organic compounds. Synthesis of the two enantiomers of (Z)-3-fluoro-4-phenyl-1-(p-tolylsulphonyl)but-3-en-2-ol through microbial reduction
BRAVO, PIERFRANCESCO;RESNATI, GIUSEPPE
1990-01-01
Abstract
The reduction of (Z)-3-fluoro-4-phenyl-1-(p-tolylsulphonyl)but-3-en-2-one with growing cultures of Geotrichum candidum and Phanerochaete chrysosporium afforded (S)- and (R)-3-fluoro-4-phenyl-1-(p-tolylsulphonyl)but-3-en-2-ol in enantiomerically pure form.File in questo prodotto:
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