1′,2′-Seco-2′-nor-nucleosides carrying a fluorine atom, instead of hydroxyl group, on C-3′ are synthesized in enantiomerically pure form, starting from (2S)-1-fluoro-3-(R)-[(4-methylphenyl)sulfinyl]-2-propanol. The nucleosides , were synthesized in enantiomerically pure form starting from (2S,RS)-.
Optically pure and fluoro substituted acyclovir analogues
BRAVO, PIERFRANCESCO;RESNATI, GIUSEPPE;
1993-01-01
Abstract
1′,2′-Seco-2′-nor-nucleosides carrying a fluorine atom, instead of hydroxyl group, on C-3′ are synthesized in enantiomerically pure form, starting from (2S)-1-fluoro-3-(R)-[(4-methylphenyl)sulfinyl]-2-propanol. The nucleosides , were synthesized in enantiomerically pure form starting from (2S,RS)-.File in questo prodotto:
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