5-Perfluoroalkylpyrazoles 6, 5-perfluoroalkylisoxazoles 11, and 4-perfluoroacylisoxazoles 13 are obtained in high chemical yields and complete site and regioselectivity through the reaction of β-perfluoroalkyl-β-dicarbonyls 2 with hydrazonyl halides 1 and halooximes 8 in the presence of bases. β-Perfluoroalkyl-β-dicarbonyls 2 are shown to be convenient precursors of 5-perfluoroalkypyrazoles 6, 5-perfluoroalkylisoxazoles 11, and 4-perfluoroacylisoxazoles 13.
An efficient entry to perfluoroalkyl substituted azoles starting from β-perfluoroalkyl-β-dicarbonyl compounds
BRAVO, PIERFRANCESCO;RESNATI, GIUSEPPE
1994-01-01
Abstract
5-Perfluoroalkylpyrazoles 6, 5-perfluoroalkylisoxazoles 11, and 4-perfluoroacylisoxazoles 13 are obtained in high chemical yields and complete site and regioselectivity through the reaction of β-perfluoroalkyl-β-dicarbonyls 2 with hydrazonyl halides 1 and halooximes 8 in the presence of bases. β-Perfluoroalkyl-β-dicarbonyls 2 are shown to be convenient precursors of 5-perfluoroalkypyrazoles 6, 5-perfluoroalkylisoxazoles 11, and 4-perfluoroacylisoxazoles 13.File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
