The title compd. is triclinic, space group P‾1, with a 12.280(3), b 10.191(3), c 6.663(2) Å, α 83.93(7), β 100.05(8), and γ 87.70(8)°; d = 1.37 for Z = 2. The final R = 0.056 for 2285 reflections. The compd., which shows pharmacol. activity in vitro, presents a puckered pyrazolidionone ring puckering angle 36.0(2)° with an N-N bond 1.445(4) Å longer than those usually found in hydrazidic moieties. Geometric and electronic features of this part of the mol. have a close similarity with those of antipyrine, a 3H-pyrazol-3-one deriv. used as an antiinflammatory drug. The at. coordinates are given
Structural studies of radical reaction products. II. 2,4-Bis(4-chlorophenyl)-5,5-dimethyl-3-pyrazolidinone
GANAZZOLI, FABIO;CITTERIO, ATTILIO;
1986-01-01
Abstract
The title compd. is triclinic, space group P‾1, with a 12.280(3), b 10.191(3), c 6.663(2) Å, α 83.93(7), β 100.05(8), and γ 87.70(8)°; d = 1.37 for Z = 2. The final R = 0.056 for 2285 reflections. The compd., which shows pharmacol. activity in vitro, presents a puckered pyrazolidionone ring puckering angle 36.0(2)° with an N-N bond 1.445(4) Å longer than those usually found in hydrazidic moieties. Geometric and electronic features of this part of the mol. have a close similarity with those of antipyrine, a 3H-pyrazol-3-one deriv. used as an antiinflammatory drug. The at. coordinates are givenFile in questo prodotto:
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