The invention concerns a silk fibroin weave structure comprising a concentric tubular outer sheath and an inner core, wherein said sheath is a woven fabric with interlaced loop and said core is a woven fabric with interlaced loop or is braided using a braiding machine. The silk fibroin used to weave the structure of the invention is a silk yarn with a linear density comprised of between approx. 40 den and approx. 640 den, preferably, the linear density is approx. 80 den or approx. 320 den. The core of the structure has a mean pore area comprised of between 0.001 and 2.000 mm 2 , while the outer sheath has a mean pore area comprised of between 0.005 and 15.000 mm 2 . The structure of the invention is used for the in vivo or in vitro regeneration of ligaments, particularly the anterior cruciate ligament, tendons, muscles and blood vessels.; Furthermore, the structure promotes in vivo and in vitro cell adhesion and proliferation.

Silk fibroin textile structures as biomimetic prosthetics for the regeneration of tissues and ligaments

TANZI, MARIA CRISTINA;FARE', SILVIA;
2009-01-01

Abstract

The invention concerns a silk fibroin weave structure comprising a concentric tubular outer sheath and an inner core, wherein said sheath is a woven fabric with interlaced loop and said core is a woven fabric with interlaced loop or is braided using a braiding machine. The silk fibroin used to weave the structure of the invention is a silk yarn with a linear density comprised of between approx. 40 den and approx. 640 den, preferably, the linear density is approx. 80 den or approx. 320 den. The core of the structure has a mean pore area comprised of between 0.001 and 2.000 mm 2 , while the outer sheath has a mean pore area comprised of between 0.005 and 15.000 mm 2 . The structure of the invention is used for the in vivo or in vitro regeneration of ligaments, particularly the anterior cruciate ligament, tendons, muscles and blood vessels.; Furthermore, the structure promotes in vivo and in vitro cell adhesion and proliferation.
2009
Seta; strutture tessili; strutture biomimetiche; legamento; rigenerazione
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11311/573620
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