In medical terms and referring to aortic arterial damage, dissection is the separation of intra-medial tissue induced by a radial tear cutting the intima (inner layer) and a portion of the underling media (middle layer). Pressurized blood pervading the tear enhances the intramural process of dissection, and may induce a subsequent formation of clots. The purpose of this study is to setup and calibrate a numerical model of arterial dissection, based on cohesive theories of fracture. The dissection model is used to characterize the critical mechanical conditions for the interlamellar propagation of a tear in the media and the influence of the reinforcing collagen fibers on the separation process.

A Numerical Study of Arterial Media Dissection Processes

PANDOLFI, ANNA MARINA
2010-01-01

Abstract

In medical terms and referring to aortic arterial damage, dissection is the separation of intra-medial tissue induced by a radial tear cutting the intima (inner layer) and a portion of the underling media (middle layer). Pressurized blood pervading the tear enhances the intramural process of dissection, and may induce a subsequent formation of clots. The purpose of this study is to setup and calibrate a numerical model of arterial dissection, based on cohesive theories of fracture. The dissection model is used to characterize the critical mechanical conditions for the interlamellar propagation of a tear in the media and the influence of the reinforcing collagen fibers on the separation process.
2010
Dissection; Anisotropy; Two-fiber reinforced tissues; Cohesive models; Finite elements
File in questo prodotto:
File Dimensione Formato  
j-2010-peelingArtery.pdf

Accesso riservato

: Post-Print (DRAFT o Author’s Accepted Manuscript-AAM)
Dimensione 667.27 kB
Formato Adobe PDF
667.27 kB Adobe PDF   Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11311/572443
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 44
  • ???jsp.display-item.citation.isi??? 38
social impact