The present study assessed in vitro the short-term cellular response to surface physico-chemical properties of a new, purposed bioactive surface treatment called BioSpark performed on simply machined and on sand-blasted titanium. Material characterisation was carried out using scanning electron microscopy, energy dispersion spectroscopy, laser profilometry, and thin film X-ray diffraction. The in vitro biological study showed a suitable cellular response with adhesion and spreading level comparable for all the tested specimens. The proliferation analysis demonstrated that all the surfaces successfully supported cellular colonisation; in particular, higher cellular proliferation activity was observed on the BioSpark-treated materials, with values higher than machined titanium. The results suggest that the BioSpark treatment represents a smart way to enhance osteoblastic cellular colonisation and thus improve osteointegration processes of machined and sandblasted titanium for orthopaedic and dental implants.
Physical and biological characterizations of a novel multiphase anodic spark deposition coating to enhance implant osseointegration
GIORDANO, CARMEN;CHIESA, ROBERTO;SANDRINI, ENRICO;CIGADA, ALBERTO;
2005-01-01
Abstract
The present study assessed in vitro the short-term cellular response to surface physico-chemical properties of a new, purposed bioactive surface treatment called BioSpark performed on simply machined and on sand-blasted titanium. Material characterisation was carried out using scanning electron microscopy, energy dispersion spectroscopy, laser profilometry, and thin film X-ray diffraction. The in vitro biological study showed a suitable cellular response with adhesion and spreading level comparable for all the tested specimens. The proliferation analysis demonstrated that all the surfaces successfully supported cellular colonisation; in particular, higher cellular proliferation activity was observed on the BioSpark-treated materials, with values higher than machined titanium. The results suggest that the BioSpark treatment represents a smart way to enhance osteoblastic cellular colonisation and thus improve osteointegration processes of machined and sandblasted titanium for orthopaedic and dental implants.File | Dimensione | Formato | |
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