The synthesis of potent inhibitors of matrix metallo proteinases (MMPs) bearing trifluoromethyl or difluoromethyl groups in purely aliphatic positions, and the effect of the incorporation of the fluoroalkyl functions on the inhibitor potency is presented.
Fluorinated Inhibitors of Matrix Metalloproteinases
L. BRUCHE';
2007-01-01
Abstract
The synthesis of potent inhibitors of matrix metallo proteinases (MMPs) bearing trifluoromethyl or difluoromethyl groups in purely aliphatic positions, and the effect of the incorporation of the fluoroalkyl functions on the inhibitor potency is presented.File in questo prodotto:
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