Today, the rapid progress in non-invasive light–matter interaction analysis is transforming the landscape of biomedical and life sciences driven by low-intensity light detection technologies. As the complexity of photonic applications continues to grow, the importance of single-photon detection techniques becomes pivotal. Among them, Time-Correlated Single-Photon Counting (TCSPC) has become the gold standard for precise, time-resolved reconstruction of rapid and faint optical signals. However, TCSPC has long been constrained by pile-up distortion, which worsens with increasing acquisition speed, typically limiting it to 5% of the excitation frequency. To overcome the operational constraints of conventional implementations, a novel TCSPC acquisition methodology has been introduced, independent of photodetector dead time, excitation intensity, and prior optical signal knowledge, still enabling distortion-free reconstruction of the measured light profiles. In this context, the development of single-photon detectors with short dead time and low timing jitter becomes crucial. This work presents a single-photon detection module based on a Silicon Photomultiplier, which delivers 750 ps FWHM output pulses with a 33.5 ps RMS IRF. Its performance is showcased through fluorescence measurements employing the constraint-free TCSPC methodology, achieving a photon count rate up to 166% of the excitation frequency with a minimal lifetime estimation error of just −1.46%.

High-Performance SiPM Detection Module for Ultra-Fast Time-Resolved Measurements

Gennaro Fratta;Piergiorgio Daniele;Giulia Acconcia;Ivan Rech
2026-01-01

Abstract

Today, the rapid progress in non-invasive light–matter interaction analysis is transforming the landscape of biomedical and life sciences driven by low-intensity light detection technologies. As the complexity of photonic applications continues to grow, the importance of single-photon detection techniques becomes pivotal. Among them, Time-Correlated Single-Photon Counting (TCSPC) has become the gold standard for precise, time-resolved reconstruction of rapid and faint optical signals. However, TCSPC has long been constrained by pile-up distortion, which worsens with increasing acquisition speed, typically limiting it to 5% of the excitation frequency. To overcome the operational constraints of conventional implementations, a novel TCSPC acquisition methodology has been introduced, independent of photodetector dead time, excitation intensity, and prior optical signal knowledge, still enabling distortion-free reconstruction of the measured light profiles. In this context, the development of single-photon detectors with short dead time and low timing jitter becomes crucial. This work presents a single-photon detection module based on a Silicon Photomultiplier, which delivers 750 ps FWHM output pulses with a 33.5 ps RMS IRF. Its performance is showcased through fluorescence measurements employing the constraint-free TCSPC methodology, achieving a photon count rate up to 166% of the excitation frequency with a minimal lifetime estimation error of just −1.46%.
2026
analog front-end electronics
correction algorithm
dead time
pile-up distortion
silicon photomultiplier
time-correlated single-photon counting
time-resolved fluorescence measurements
timing jitter
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11311/1330966
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