Label-free morpho-molecular imaging circumvents the invasiveness of conventional omics while rapidly delivering quantitative phenotypes of live cells and three-dimensional cell aggregates. By integrating phase tomography with spontaneous and coherent Raman spectroscopy, we reveal and track elusive yet critical cell states in developmental and cancer biology.

Label-free morpho-molecular live-cell phenotyping propels biological discovery

Bresci, Arianna;Polli, Dario;
2026-01-01

Abstract

Label-free morpho-molecular imaging circumvents the invasiveness of conventional omics while rapidly delivering quantitative phenotypes of live cells and three-dimensional cell aggregates. By integrating phase tomography with spontaneous and coherent Raman spectroscopy, we reveal and track elusive yet critical cell states in developmental and cancer biology.
2026
Proceedings of SPIE - The International Society for Optical Engineering
Cancer Biology
Developmental Biology
Label-free Biomedical Imaging
Live-Cell Imaging
Raman Spectroscopy
Stimulated Raman Scattering
Tomographic Phase Microscopy
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11311/1310437
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