Design and Implementation of a Wearable Electrochemical Sweat Sensing Platform on Smart Eyeglasses

A miniature wireless electronic system is presented for application to wearable electrochemical detection of ions, such as potassium, and metabolites in sweat. It features ultra-low-power electronics that communicate via Bluetooth Low Energy. Thanks to low power consumption (below 500μA) and flexible PCB gold-finished electrodes for potentiometry, the MCU-based system can be integrated, as here demonstrated, into eye glasses for continuous monitoring (12 days with button batteries) with sub-mM resolution of the target ionic species. An original feature of the system is the anlaysis activation upon filling of the microfluidic sweat collection chamber (approximately 4.8 μL of sweat and endowed with a self-siphon) in contact with the temple.