Monitoring of VOCs in Indoor Air Quality: Definition of an ISO 16000-Based Sampling Protocol for Inpatient Wards

Indoor Air Quality (IAQ) is a major public health concern, as prolonged exposure to indoor environments can significantly affect users’ well-being. In this context, the research proposes a sampling protocol, developed in compliance with ISO 16000 principles, for the assessment of key chemical and physical parameters influencing air quality in inpatient rooms. These spaces host fragile users, while also requiring adequate protection for healthcare staff. Referring to the scope of the paper, the study outlines a comprehensive methodology for monitoring selected volatile organic compounds (VOCs) and microclimatic factors—temperature and relative humidity—using passive samplers and/or active sensors. The protocol also integrates outdoor measurements to better understand the contribution of internal emission sources. Monitoring activities are scheduled over one year, with regular sampling campaigns (at least one week per month) to analyze seasonal variations and long-term trends. The flexible structure of the protocol allows it to be adapted to different research objectives and types of healthcare facilities. Overall, the proposed approach provides a replicable framework for assessing IAQ in healthcare settings and identifying the main factors affecting indoor environmental performance. This supports improvements in both environmental quality and health protection within healing spaces.