Optical stimulation of living cells is an innovative and successful tool, having a significant impact on neuroscience. A recently synthesized amphiphilic azobenzene, named Ziapin2, has been developed exploiting a non-covalent approach for targeting the membrane and achieving cell photostimulation. Here, we investigate, using both experimental data and mathematical modelling, the effect of repetitive light stimulation on the cell response. We discuss some possible explanations for the drop in the stimulation efficiency in reiterated stimulation processes.
The effects of reiterated cell photo-stimulation with an azobenzene
Magni A.;Vurro V.;Lanzani G.
2023-01-01
Abstract
Optical stimulation of living cells is an innovative and successful tool, having a significant impact on neuroscience. A recently synthesized amphiphilic azobenzene, named Ziapin2, has been developed exploiting a non-covalent approach for targeting the membrane and achieving cell photostimulation. Here, we investigate, using both experimental data and mathematical modelling, the effect of repetitive light stimulation on the cell response. We discuss some possible explanations for the drop in the stimulation efficiency in reiterated stimulation processes.File in questo prodotto:
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