Hydrogels are widely investigated to develop 3D in vitro models for mimicking tissue microenvironment since their properties well match soft tissues ones. One concern is the lack of an adequate channel network, mimicking the tissue vascularization. Optimizing a vascularization strategy still remains challenging. We optimized and characterized a GelMA/Pluronic combination by using embedded 3D printing for the realization of a channel network in a GelMA scaffold.

Embedded 3D printing for the development of perfusable in vitro 3D model of soft tissue

Pitton M.;Ancona E.;Fare' S.
2023-01-01

Abstract

Hydrogels are widely investigated to develop 3D in vitro models for mimicking tissue microenvironment since their properties well match soft tissues ones. One concern is the lack of an adequate channel network, mimicking the tissue vascularization. Optimizing a vascularization strategy still remains challenging. We optimized and characterized a GelMA/Pluronic combination by using embedded 3D printing for the realization of a channel network in a GelMA scaffold.
2023
Embedded 3D printing; GelMA; 3D in vitro model; Soft tissue; Vascularization
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11311/1234511
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