In the recent years, Bioresorbable Vascular Scaffolds (BVS) for the treatment of atherosclerosis have been introduced. InSilc is a cloud based in silico clinical trial (ISCT) platform for drug-eluting BVS. The platform integrates multidisciplinary and multiscale models predicting the BVS performance. In this study, we present a use case scenario and demonstrate the functioning of the individual modules and of the whole pipeline and the ability to predict BVS short, medium, long-term outcomes.

Design and implementation of in silico clinical trial for Bioresorbable Vascular Scaffolds

Antonini L.;Petrini L.;Pennati G.;
2020

Abstract

In the recent years, Bioresorbable Vascular Scaffolds (BVS) for the treatment of atherosclerosis have been introduced. InSilc is a cloud based in silico clinical trial (ISCT) platform for drug-eluting BVS. The platform integrates multidisciplinary and multiscale models predicting the BVS performance. In this study, we present a use case scenario and demonstrate the functioning of the individual modules and of the whole pipeline and the ability to predict BVS short, medium, long-term outcomes.
Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
978-1-7281-1990-8
Clinical Trials as Topic
Computer Simulation
Tissue Scaffolds
Treatment Outcome
Absorbable Implants
Drug-Eluting Stents
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11311/1210508
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