The introduction of Bioresorbable Vascular Scaffolds (BVS) has revolutionized the treatment of atherosclerosis. InSilc is an in silico clinical trial (ISCT) platform in a Cloud-based environment used for the design, development and evaluation of BVS. Advanced multi-disciplinary and multiscale models are integrated in the platform towards predicting the short/acute and medium/long term scaffold performance. In this study, InSilc platform is employed in a use case scenario and demonstrates how the whole in silico pipeline allows the interpretation of the effect of the arterial anatomy configuration on stent implantation.

An in silico trials platform for the evaluation of effect of the arterial anatomy configuration on stent implantation

Antonini L.;Pennati G.;Petrini L.;
2021

Abstract

The introduction of Bioresorbable Vascular Scaffolds (BVS) has revolutionized the treatment of atherosclerosis. InSilc is an in silico clinical trial (ISCT) platform in a Cloud-based environment used for the design, development and evaluation of BVS. Advanced multi-disciplinary and multiscale models are integrated in the platform towards predicting the short/acute and medium/long term scaffold performance. In this study, InSilc platform is employed in a use case scenario and demonstrates how the whole in silico pipeline allows the interpretation of the effect of the arterial anatomy configuration on stent implantation.
Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
978-1-7281-1179-7
Absorbable Implants
Clinical Trials as Topic
Humans
Time Factors
Angioplasty, Balloon, Coronary
Drug-Eluting Stents
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11311/1210507
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