Mathematical and numerical models of atherosclerotic plaque progression in carotid arteries

We propose a mathematical model for the description of plaque progression in carotid arteries. This is based on the coupling of a fluid-structure interaction problem, arising between blood and vessel wall, and differential problems for the cellular evolution. A numerical model is also proposed. This is based on the splitting of the coupled problem based on a suitable strategy to manage the multiscale-in-time nature of the problem. We present some preliminary numerical results both in ideal and real scenarios.