The present invention relates to a cartridge adapted to house at least one biological sample therein, wherein said cartridge comprises at least two overlapping layers, wherein said layers consist of: - at least one layer consisting of highly hydrophobic, inert, and biocompatible material, with contact angle Θc ≥ 90°, hydrophobic layer; - optionally, at least one layer of double-sided adhesive material; wherein, in the absence of said at least one layer of doublesided adhesive material, said overlapping layers are connected together by chemical and/or physical bonding; wherein each of said overlapping layers has at least one inner hole and said at least one inner hole is pervious when said layers overlap one another; wherein said at least one inner hole is closed by said at least one biological sample, where loaded in said cartridge. The present invention further relates to a fluidic device and a fluidic devices-support station complex comprising said cartridge, and to the use thereof in static and/or dynamic bicompartmental biological cultures.

Device for biological cultures

G. B. Fiore;M. Soncini;L. P. Coppadoro;M. Piola;
2021-01-01

Abstract

The present invention relates to a cartridge adapted to house at least one biological sample therein, wherein said cartridge comprises at least two overlapping layers, wherein said layers consist of: - at least one layer consisting of highly hydrophobic, inert, and biocompatible material, with contact angle Θc ≥ 90°, hydrophobic layer; - optionally, at least one layer of double-sided adhesive material; wherein, in the absence of said at least one layer of doublesided adhesive material, said overlapping layers are connected together by chemical and/or physical bonding; wherein each of said overlapping layers has at least one inner hole and said at least one inner hole is pervious when said layers overlap one another; wherein said at least one inner hole is closed by said at least one biological sample, where loaded in said cartridge. The present invention further relates to a fluidic device and a fluidic devices-support station complex comprising said cartridge, and to the use thereof in static and/or dynamic bicompartmental biological cultures.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11311/1208353
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