Introduction: Severe Uncertainty in Science, Medicine, and Technology

This Special Issue titled "Severe Uncertainty in Science, Medicine and Technology" aims to shed new light on the understanding of severe uncertainty and its multifaceted implications. The main idea of the papers of this collection is that, despite possible sophisticated statistical judgments towards future risks in science, medicine, and technology, severe forms of uncertainty still exist.While ignorance is usually assumed to be a total absence of knowledge, uncertainty often refers to the incompleteness of knowledge or information. In its extreme form, this is called "severe uncertainty" but is also known as "fundamental," "radical," "deep," "great," or "genuine" uncertainty.