3-Hydroxy-2-pyrone is a valuable building block of many molecules. The syntheses until now proposed to prepare this compound are not ecofriendly and are unsuitable for large scale productions. We now report an easy gram scale preparation of this pyrone, by simple heating in water of bio-based 6-caboxylic-3-hydroxy-2-pyrone derivatives. The full process can be also performed by a telescopic reaction starting from galactaric acid (mucic acid).

A facile synthesis in aqueous medium of 3-hydroxy-2-pyrone from aldaric acids or their derivatives

Leonardi, Gabriella;Truscello, Ada;Mondrone, Giovanni G.;Sebastiano, Roberto
2022

Abstract

3-Hydroxy-2-pyrone is a valuable building block of many molecules. The syntheses until now proposed to prepare this compound are not ecofriendly and are unsuitable for large scale productions. We now report an easy gram scale preparation of this pyrone, by simple heating in water of bio-based 6-caboxylic-3-hydroxy-2-pyrone derivatives. The full process can be also performed by a telescopic reaction starting from galactaric acid (mucic acid).
Green chemistry, 2-pyrones, biomass, aldaric acid
File in questo prodotto:
File Dimensione Formato  
Results in Chemistry 4 (2022)100280.pdf

accesso aperto

: Publisher’s version
Dimensione 3.75 MB
Formato Adobe PDF
3.75 MB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11311/1195098
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 0
  • ???jsp.display-item.citation.isi??? ND
social impact