In spite of the current relevance of the topic, there is no universally recognized knowledge base about SARS-CoV-2 variants; viral sequences deposited at recognized repositories are still very few, and the process of tracking new variants is not coordinated. CoV2K is a manually curated knowledge base providing an organized collection of information about SARS-CoV-2 variants, extracted from the scientific literature; it features a taxonomy of variant impacts, organized according to three main categories (protein stability, epidemiology, and immunology) and including levels for these effects (higher, lower, null) resulting from a coherent interpretation of research articles.

CoV2K: A Knowledge Base of SARS-CoV-2 Variant Impacts

Al Khalaf, Ruba;Alfonsi, Tommaso;Ceri, Stefano;Bernasconi, Anna
2021-01-01

Abstract

In spite of the current relevance of the topic, there is no universally recognized knowledge base about SARS-CoV-2 variants; viral sequences deposited at recognized repositories are still very few, and the process of tracking new variants is not coordinated. CoV2K is a manually curated knowledge base providing an organized collection of information about SARS-CoV-2 variants, extracted from the scientific literature; it features a taxonomy of variant impacts, organized according to three main categories (protein stability, epidemiology, and immunology) and including levels for these effects (higher, lower, null) resulting from a coherent interpretation of research articles.
2021
Research Challenges in Information Science. RCIS 2021.
978-3-030-75017-6
978-3-030-75018-3
SARS-CoV-2, Variant impact, COVID-19, Knowledge base, Data integration, Statistical testing
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11311/1172289
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