Device (1) for the quantification of corpusculated and non-corpusculated components (3, 3’, 3”) in a solution containing a blood sample comprising: at least one pair of detection electrodes (4, 4’, 5, 5’, 6, 6’, 34, 34’), said at least one pair of detection electrodes (4, 4’, 5, 5’, 6, 6’, 34, 34’) comprising at least one first electrode (4, 5, 6, 34) connected with a first input apt to receive a first signal in input (V+) and a second electrode (4’, 5’, 6’, 34’); at least one pair of reference electrodes (7, 7’, 8, 8’, 9, 9’, 37, 37’), said at least one pair of reference electrodes (7, 7’, 8, 8’, 9, 9’, 37, 37’) comprising a first electrode (7, 8, 9, 37) connected with a second input configured to receive a second signal in input (V-) of opposite polarity to the first input signal (V+) and a second electrode (7’, 8’, 9’, 37’) connected to the second electrode (4’, 5’, 6’, 34’) of said at least one pair of detection electrodes (4, 4’, 5, 5’, 6, 6’, 34, 34’), in a common point wherefrom an output signal (Out) is picked up; at least one concentrator (10, 10’, 10”, 14, 14’, 14”) of ferromagnetic material, configured to co-operate with a magnetic field external to the device (1), in such a way as to cause the concentration of said components (3, 3’, 3’’) on said at least one pair of detection electrodes (4, 4’, 5, 5’, 6, 6’, 34, 34’); a substrate (11) configured for the housing of: said at least one pair of detection electrodes (4, 4’, 5, 5’, 6, 6’, 34, 34’), said at least one pair of reference electrodes (7, 7’, 8, 8’, 9, 9’, 37, 37’) and said at least one concentrator (10, 10’, 10”, 14, 14’, 14’’); a support (12) configured to collect a sample of blood or of solution containing blood; at least one spacer element (13, 13’) configured to confine in the plane of the substrate the blood sample and to distance said substrate (11) from said support (12).

DEVICE AND METHOD FOR THE QUANTIFICATION OF CORPUSCULATED AND NON-CORPUSCULATED BLOOD COMPONENTS

Riccardo Bertacco;Marco Giacometti;Giorgio Ferrari;Daniela Petti;Edoardo Albisetti
2018

Abstract

Device (1) for the quantification of corpusculated and non-corpusculated components (3, 3’, 3”) in a solution containing a blood sample comprising: at least one pair of detection electrodes (4, 4’, 5, 5’, 6, 6’, 34, 34’), said at least one pair of detection electrodes (4, 4’, 5, 5’, 6, 6’, 34, 34’) comprising at least one first electrode (4, 5, 6, 34) connected with a first input apt to receive a first signal in input (V+) and a second electrode (4’, 5’, 6’, 34’); at least one pair of reference electrodes (7, 7’, 8, 8’, 9, 9’, 37, 37’), said at least one pair of reference electrodes (7, 7’, 8, 8’, 9, 9’, 37, 37’) comprising a first electrode (7, 8, 9, 37) connected with a second input configured to receive a second signal in input (V-) of opposite polarity to the first input signal (V+) and a second electrode (7’, 8’, 9’, 37’) connected to the second electrode (4’, 5’, 6’, 34’) of said at least one pair of detection electrodes (4, 4’, 5, 5’, 6, 6’, 34, 34’), in a common point wherefrom an output signal (Out) is picked up; at least one concentrator (10, 10’, 10”, 14, 14’, 14”) of ferromagnetic material, configured to co-operate with a magnetic field external to the device (1), in such a way as to cause the concentration of said components (3, 3’, 3’’) on said at least one pair of detection electrodes (4, 4’, 5, 5’, 6, 6’, 34, 34’); a substrate (11) configured for the housing of: said at least one pair of detection electrodes (4, 4’, 5, 5’, 6, 6’, 34, 34’), said at least one pair of reference electrodes (7, 7’, 8, 8’, 9, 9’, 37, 37’) and said at least one concentrator (10, 10’, 10”, 14, 14’, 14’’); a support (12) configured to collect a sample of blood or of solution containing blood; at least one spacer element (13, 13’) configured to confine in the plane of the substrate the blood sample and to distance said substrate (11) from said support (12).
Malaria, diagnostic test
File in questo prodotto:
File Dimensione Formato  
WO2019_01691.pdf

accesso aperto

Descrizione: Testo della domanda di brevetto internazionale PCT
: Publisher’s version
Dimensione 1.17 MB
Formato Adobe PDF
1.17 MB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11311/1126845
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact