A multivariate method integrating time-domain and space-domain techniques of near-infrared spectroscopy is proposed for simultaneously retrieving the absolute quantities of optical scattering and absorption properties in tissues. The concept is theoretically demonstrated by Monte-Carlo simulations in the homogenous case, and then applied on two-layer liquid phantoms. The deviations from nominal values are typically less than 6% for absorption coefficients in both layers

Spatially-enhanced time-domain NIRS for determination of optical properties in layered structures

Rinaldo Cubeddu;Sanathana Konugolu Venkata Sekar;Antonio Pifferi;
2019-01-01

Abstract

A multivariate method integrating time-domain and space-domain techniques of near-infrared spectroscopy is proposed for simultaneously retrieving the absolute quantities of optical scattering and absorption properties in tissues. The concept is theoretically demonstrated by Monte-Carlo simulations in the homogenous case, and then applied on two-layer liquid phantoms. The deviations from nominal values are typically less than 6% for absorption coefficients in both layers
Clinical and Preclinical Optical Diagnostics II
9781510628397
Absorption coefficient; Analytical techniques; Attenuation coefficient; Near infrared radiation; Optical absorption; Optical properties
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11311/1125039
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