A multivariate method integrating time-domain and space-domain techniques of near-infrared spectroscopy is proposed for simultaneously retrieving the absolute quantities of optical scattering and absorption properties in tissues. The concept is theoretically demonstrated by Monte-Carlo simulations in the homogenous case, and then applied on two-layer liquid phantoms. The deviations from nominal values are typically less than 6% for absorption coefficients in both layers
Spatially-enhanced time-domain NIRS for determination of optical properties in layered structures
Rinaldo Cubeddu;Sanathana Konugolu Venkata Sekar;Antonio Pifferi;
2019-01-01
Abstract
A multivariate method integrating time-domain and space-domain techniques of near-infrared spectroscopy is proposed for simultaneously retrieving the absolute quantities of optical scattering and absorption properties in tissues. The concept is theoretically demonstrated by Monte-Carlo simulations in the homogenous case, and then applied on two-layer liquid phantoms. The deviations from nominal values are typically less than 6% for absorption coefficients in both layersFile in questo prodotto:
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