Septic shock (SS) patients often show elevated heart rate (HR) despite resuscitation and this condition is considered an early manifestation of myocardial dysfunction, due to an impairment of autonomic nervous system (ANS). We aimed at proposing a mathematical model to assess the autonomic control of ventricular contractility (VC) and HR to track changes in heart functionality during an experimental animal model of SS and resuscitation.
A mathematical model of dP/dt max for the evaluation of the dynamic control of heart contractility in septic shock
Carrara, Marta;Baselli, Giuseppe;Ferrario, Manuela
2019-01-01
Abstract
Septic shock (SS) patients often show elevated heart rate (HR) despite resuscitation and this condition is considered an early manifestation of myocardial dysfunction, due to an impairment of autonomic nervous system (ANS). We aimed at proposing a mathematical model to assess the autonomic control of ventricular contractility (VC) and HR to track changes in heart functionality during an experimental animal model of SS and resuscitation.File in questo prodotto:
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