A novel total synthesis leading to the carbazole alkaloid carbazomycin G was designed and developed. The outlined synthetic route is composed of twelve synthetic steps including the transformations of the very first simple substrate and intermediates. In order to realize the designed synthesis, in total six new synthetic methods were developed and implemented in the new total synthesis, which afforded target molecule in an overall yield of 8.3%.

Carbazomycin G: Method development and total synthesis

Gambarotti, Cristian;
2018-01-01

Abstract

A novel total synthesis leading to the carbazole alkaloid carbazomycin G was designed and developed. The outlined synthetic route is composed of twelve synthetic steps including the transformations of the very first simple substrate and intermediates. In order to realize the designed synthesis, in total six new synthetic methods were developed and implemented in the new total synthesis, which afforded target molecule in an overall yield of 8.3%.
2018
Synthetic methods, Total synthesis, Cross-coupling, C–H activation, C–N bond formation, Redox reactions
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11311/1054488
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