Sfoglia per Autore
New stereospecific synthesis of Tesaglitazar and Navaglitazar precursors
2009-01-01 Brenna, MARIA ELISABETTA; Fuganti, Claudio; Gatti, FRANCESCO GILBERTO; Parmeggiani, Fabio
Enzyme-mediated synthesis of EEHP and EMHP, useful pharmaceutical intermediates of PPAR agonists
2009-01-01 Brenna, MARIA ELISABETTA; Fuganti, Claudio; Gatti, FRANCESCO GILBERTO; Parmeggiani, Fabio
Productivity enhancement of biocatalysed enantioselective C=C reductions: the bioreduction of alphabrocine from whole cells to isolated enzymes
2011-01-01 Parmeggiani, Fabio
Enantioselective C=C bond reduction of unsaturated α-chloro esters by old yellow enzymes
2011-01-01 Brenna, MARIA ELISABETTA; G., Fronza; Fuganti, Claudio; D., Monti; Parmeggiani, Fabio
Biocatalyzed enantioselective reduction of activated C=C bonds: synthesis of enantiomerically enriched alpha -halo-beta -arylpropionic acids.
2011-01-01 Brenna, MARIA ELISABETTA; Gatti, FRANCESCO GILBERTO; A., Manfredi; D., Monti; Parmeggiani, Fabio
Preparation and Luminescence Thermochromism of Tetranuclear Copper(I)–Pyridine–Iodide Clusters
2012-01-01 Parmeggiani, Fabio; Sacchetti, Alessandro
Enoate Reductase-Mediated Preparation of Methyl (S)-2-Bromobutanoate, a Useful Key Intermediate for the Synthesis of Chiral Active Pharmaceutical Ingredients
2012-01-01 Brenna, MARIA ELISABETTA; Gatti, FRANCESCO GILBERTO; A., Manfredi; D., Monti; Parmeggiani, Fabio
Biotechnological Development of a Practical Synthesis of Ethyl (S)-2-Ethoxy-3-(p-methoxyphenyl)propanoate (EEHP): Over 100-Fold Productivity Increase from Yeast Whole Cells to Recombinant Isolated Enzymes
2012-01-01 M., Bechtold; Brenna, MARIA ELISABETTA; C., Femmer; Gatti, FRANCESCO GILBERTO; S., Panke; Parmeggiani, Fabio; Sacchetti, Alessandro
Stereochemical outcome of the biocatalyzed reduction of activated tetrasubstituted olefins by old yellow enzymes 1-3
2012-01-01 Brenna, MARIA ELISABETTA; Gatti, FRANCESCO GILBERTO; D., Monti; Parmeggiani, Fabio; S., Serra
Cascade Coupling of Ene Reductases with Alcohol Dehydrogenases: Enantioselective Reduction of Prochiral Unsaturated Aldehydes
2012-01-01 Brenna, MARIA ELISABETTA; Gatti, FRANCESCO GILBERTO; Daniela, Monti; Parmeggiani, Fabio; Sacchetti, Alessandro
On the stereochemistry of the Baker's Yeast-mediated reduction of regioisomeric unsaturated aldehydes: Examples of enantioselectivity switch promoted by substrate-engineering
2012-01-01 Brenna, MARIA ELISABETTA; G., Fronza; Fuganti, Claudio; Gatti, FRANCESCO GILBERTO; A., Manfredi; Parmeggiani, Fabio; P., Ronchi
Steric Effects on the Stereochemistry of Old Yellow Enzyme-Mediated Reductions of Unsaturated Diesters: Flipping of the Substrate within the Enzyme Active Site Induced by Structural Modifications
2012-01-01 Brenna, MARIA ELISABETTA; Gatti, FRANCESCO GILBERTO; A., Manfredi; D., Monti; Parmeggiani, Fabio
Productivity enhancement of C=C bioreductions by coupling the in situ substrate feeding product removal technology with isolated enzymes.
2012-01-01 Brenna, MARIA ELISABETTA; Gatti, FRANCESCO GILBERTO; D., Monti; Parmeggiani, Fabio; Sacchetti, Alessandro
Enoate Reductases for Reduction of Electron Deficient Alkenes
2012-01-01 Hall, M.; Winkler, C. K.; Tasnádi, G.; Faber, K.; Brenna, MARIA ELISABETTA; Gatti, FRANCESCO GILBERTO; Parmeggiani, F.; Buzzini, P.; Goretti, M.; Ponzoni, C.; Caselli, E.; Branda, E.; Cramarossa, M. R.; Turchetti, B.; Forti, L.; Walton, A. Z.; Sullivan, Bradford T.; Stewart, J. D.; Sortino, M. A.; Zacchino, S. A.
Biocatalysed reduction of carboxylic acids and esters to primary alcohols
2013-01-01 Brenna, MARIA ELISABETTA; F., Cannavale; M., Crotti; Parmeggiani, Fabio; A., Pugliese; A., Romagnolo; F., Spina; C. G., Varese
ENE-REDUCTASE-MEDIATED REDUCTION OF beta-CYANO-alpha,beta-UNSATURATED ESTERS FOR THE SYNTHESIS OF CHIRAL BUILDING BLOCKS
2013-01-01 S., Santangelo; Brenna, MARIA ELISABETTA; Gatti, FRANCESCO GILBERTO; A., Manfredi; D., Monti; Parmeggiani, Fabio; D., Zampieri
Synthesis of Robalzotan, Ebalzotan, and Rotigotine Precursors via the Stereoselective Multienzymatic Cascade Reduction of α,β-Unsaturated Aldehydes
2013-01-01 Brenna, MARIA ELISABETTA; Gatti, FRANCESCO GILBERTO; Malpezzi, Luciana; Daniela, Monti; Parmeggiani, Fabio; Sacchetti, Alessandro
Substrate scope and synthetic applications of the enantioselective reduction of α-alkyl-β-arylenones mediated by Old Yellow Enzymes
2013-01-01 Brenna, MARIA ELISABETTA; Sara Lucia, Cosi; Erica Elisa, Ferrandi; Gatti, FRANCESCO GILBERTO; Daniela, Monti; Parmeggiani, Fabio; Sacchetti, Alessandro
Old Yellow Enzyme – mediated reduction of unsaturated diesters and cyanoesters for applications in organic synthesis: stereochemical analysis of the reaction
2013-01-01 Brenna, MARIA ELISABETTA; Gatti, FRANCESCO GILBERTO; A., Manfredi; D., Monti; Parmeggiani, Fabio; D. S., Zampieri
Fungal laccases and enoate reductases as biocatalysts of fine chemical transformations
2013-01-01 A., Romagnolo; F., Spina; D., Carusetta; L., Nerva; M. R., Cramarossa; Parmeggiani, Fabio; L., Forti; Brenna, MARIA ELISABETTA; G. C. Varese G., C.
Old Yellow Enzyme-mediated reduction of β-cyano-α,β- unsaturated esters for the synthesis of chiral building blocks: Stereochemical analysis of the reaction
2013-01-01 Brenna, MARIA ELISABETTA; Gatti, FRANCESCO GILBERTO; A., Manfredi; D., Monti; Parmeggiani, Fabio
Fear of the Dark: Diazo Printing by Photochemical Decomposition of Aryldiazonium Tetrafluoroborates
2014-01-01 Parmeggiani, Fabio
Multi-enzymatic stereoselective synthesis of chiral synthons and pharmaceutical intermediates
2014-01-01 D., Monti; Brenna, MARIA ELISABETTA; Gatti, FRANCESCO GILBERTO; Parmeggiani, Fabio; Sacchetti, Alessandro
Enantioselective Synthesis of (R)-2-Arylpropanenitriles Catalysed by Ene-Reductases in Aqueous Media and in Biphasic Ionic Liquid–Water Systems
2014-01-01 Brenna, MARIA ELISABETTA; M., Crotti; Gatti, FRANCESCO GILBERTO; A., Manfredi; D., Monti; Parmeggiani, Fabio; S., Santangelo; D., Zampieri
Rationalisation of the stereochemical outcome of ene-reductase-mediated bioreduction of α,β-difunctionalised alkenes
2014-01-01 Brenna, MARIA ELISABETTA; M., Crotti; Gatti, FRANCESCO GILBERTO; A., Manfredi; D., Monti; Parmeggiani, Fabio; A., Pugliese; D., Zampieri
Cascade Coupling of Ene-Reductases and w-Transaminases for the Stereoselective Synthesis of Diastereomerically Enriched Amines
2015-01-01 Monti, Daniela; Forchin, Maria Chiara; Crotti, Michele; Parmeggiani, Fabio; Gatti, FRANCESCO GILBERTO; Brenna, MARIA ELISABETTA; Riva, Sergio
Investigation of the stereochemical course of ene reductase-catalysed reactions by deuterium labelling
2015-01-01 Brenna, MARIA ELISABETTA; Fronza, Giovanni; Fuganti, Claudio; Parmeggiani, Fabio
Productivity Improvement of the Bioreduction of α,β-Unsaturated Aldehydes by Coupling of the In Situ Substrate Feeding Product Removal (SFPR) Strategy with Isolated Enzymes
2015-01-01 Brenna, MARIA ELISABETTA; Gatti, FRANCESCO GILBERTO; Daniela, Monti; Parmeggiani, Fabio; Sacchetti, Alessandro
Substrate-engineering approach to the stereoselective chemo-multienzymatic cascade synthesis of Nicotiana tabacum lactone
2015-01-01 Brenna, MARIA ELISABETTA; Gatti, FRANCESCO GILBERTO; Monti, Daniela; Parmeggiani, Fabio; Sacchetti, Alessandro; Valoti, Jessica
Opposite Enantioselectivity in the Bioreduction of (Z)-beta-Aryl-eta-cyanoacrylates Mediated by the Tryptophan 116 Mutants of Old Yellow Enzyme 1: Synthetic Approach to (R)- and (S)-beta-Aryl-gamma-lactams
2015-01-01 Brenna, MARIA ELISABETTA; Crotti, Michele; Gatti, FRANCESCO GILBERTO; Monti, Daniela; Parmeggiani, Fabio; Powell, Robert W.; Santangelo, Sara; Stewart, Jon D.
Multi-enzyme cascade synthesis of the most odorous stereoisomers of the commercial odorant Muguesia
2015-01-01 Brenna, MARIA ELISABETTA; Crotti, Michele; Gatti, FRANCESCO GILBERTO; Monti, Daniela; Parmeggiani, Fabio; Pugliese, Andrea; Santangelo, Sara
A Rapid and High-Throughput Assay for the Estimation of Conversions of Ene-Reductase-Catalysed Reactions
2015-01-01 Forchin, Maria Chiara; Crotti, Michele; Gatti, FRANCESCO GILBERTO; Parmeggiani, Fabio; Brenna, MARIA ELISABETTA; Monti, Daniela
Biocatalysed reduction of carboxylic acids to primary alcohols in aqueous medium: A novel synthetic capability of the zygomycete fungus Syncephalastrum racemosum
2015-01-01 Brenna, MARIA ELISABETTA; Cannavale, Flavia; Crotti, Michele; Parmeggiani, Fabio; Romagnolo, Alice; Spina, Federica; Varese, Giovanna Cristina
Identification of fungal ene-reductase activity by means of a functional screening
2015-01-01 A., Romagnolo; F., Spina; Brenna, MARIA ELISABETTA; M., Crotti; F., Parmeggiani Varese; G. C., A.
Synthesis of Enantiomerically Enriched 2-Hydroxymethylalkanoic Acids by Oxidative Desymmetrisation of Achiral 1,3-Diols Mediated by Acetobacter aceti
2016-01-01 Brenna, MARIA ELISABETTA; Cannavale, Flavia; Crotti, Michele; Gatti, FRANCESCO GILBERTO; Migliazza, G.; Molinari, F.; Parmeggiani, Fabio; Romano, D.
Substrate Scope Evaluation of the Enantioselective Reduction of β-Alkyl-β-arylnitroalkenes by Old Yellow Enzymes 1-3 for Organic Synthesis Applications
2016-01-01 Bertolotti, Mattia; Brenna, MARIA ELISABETTA; Crotti, Michele; Gatti, FRANCESCO GILBERTO; Monti, D.; Parmeggiani, Fabio; Santangelo, Sara
Biotechnological production of flavors
2016-01-01 Brenna, MARIA ELISABETTA; Parmeggiani, Fabio
One-pot multi-enzymatic synthesis of the four stereoisomers of 4-methylheptan-3-ol
2017-01-01 Brenna, E.; Crotti, M.; Gatti, F. G.; Monti, D.; Parmeggiani, F.; Pugliese, A.
One-Pot Biocatalytic Double Oxidation of α-Isophorone for the Synthesis of Ketoisophorone
2017-01-01 Tavanti, M.; Parmeggiani, F.; Castellanos, J. R. G.; Mattevi, A.; Turner, N. J.
Kinetic Resolution of Aromatic β-Amino Acids Using a Combination of Phenylalanine Ammonia Lyase and Aminomutase Biocatalysts
2017-01-01 Weise, N. J.; Ahmed, S. T.; Parmeggiani, F.; Turner, N. J.
Applications of phenylalanine ammonia lyases in synthesis: Access to enantiopure arylalanines from laboratory scale to industrial production
2017-01-01 Ahmed, S. T.; Weise, N. J.; Parmeggiani, F.; Turner, N. J.
Zymophore identification enables the discovery of novel phenylalanine ammonia lyase enzymes
2017-01-01 Weise, N. J.; Ahmed, S. T.; Parmeggiani, F.; Galman, J. L.; Dunstan, M. S.; Charnock, S. J.; Leys, D.; Turner, N. J.
Asymmetric Bioreduction of beta-Acylaminonitroalkenes: Easy Access to Chiral Building Blocks with Two Vicinal Nitrogen-Containing Functional Groups
2017-01-01 Brenna, MARIA ELISABETTA; Crotti, Michele; Gatti, Francesco G.; Monti, Daniela; Parmeggiani, Fabio; Santangelo, Sara
Real-time screening of biocatalysts in live bacterial colonies
2017-01-01 Yan, C.; Parmeggiani, F.; Jones, E. A.; Claude, E.; Hussain, S. A.; Turner, N. J.; Flitsch, S. L.; Barran, P. E.
Biocatalytic transamination with near-stoichiometric inexpensive amine donors mediated by bifunctional mono- and di-amine transaminases
2017-01-01 Galman, J. L.; Slabu, I.; Weise, N. J.; Iglesias, C.; Parmeggiani, F.; Lloyd, R. C.; Turner, N. J.
Adenylation Activity of Carboxylic Acid Reductases Enables the Synthesis of Amides
2017-01-01 Wood, A. J. L.; Weise, N. J.; Frampton, J. D.; Dunstan, M. S.; Hollas, M. A.; Derrington, S. R.; Lloyd, R. C.; Quaglia, D.; Parmeggiani, F.; Leys, D.; Turner, N. J.; Flitsch, S. L.
Biocatalytic synthesis of chiral cyclic gamma-oxoesters by sequential C-H hydroxylation, alcohol oxidation and alkene reduction
2017-01-01 Brenna, MARIA ELISABETTA; Crotti, Michele; Gatti, Francesco G.; Daniela, Monti; Parmeggiani, Fabio; Pugliese, Andrea; Tentori, Francesca
Discovery and Investigation of Mutase-like Activity in a Phenylalanine Ammonia Lyase from Anabaena variabilis
2018-01-01 Weise, N. J.; Parmeggiani, F.; Ahmed, S. T.; Turner, N. J.
Biomimetic synthesis of 2-substituted N-heterocycle alkaloids by one-pot hydrolysis, transamination and decarboxylative Mannich reaction
2018-01-01 Galman, J. L.; Slabu, I.; Parmeggiani, F.; Turner, N. J.
Synthetic and therapeutic applications of ammonia-lyases and aminomutases
2018-01-01 Parmeggiani, F.; Weise, N. J.; Ahmed, S. T.; Turner, N. J.
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