Commercially available hydrophobic porphyrins are investigated as an environmentally friendly catalytic system for iron-mediated atom transfer radical polymerization (ATRP) of poly(ethylene glycol) monomethyl ether methacrylate (PEGMA). Polymerizations in organic solvent are optimized using activators generated by electron transfer (AGET ATRP), based on iron(III)-porphyrin complexes, and tin(II) 2-ethyl hexanoate or ascorbic acid as a reducing agent. Copper-free PPEGMA macromolecules are obtained with high conversion, controlled molecular weight, and polydispersity index compared with standard copper-based ATRP. The facile preparation and availability of the catalyst, together with its expected low toxicity, represent clear advantages for the synthesis of PPEGMA-based materials for biomedical use.

AGET ATRP of Poly[poly(ethylene glycol) methyl ether methacrylate] Catalyzed by Hydrophobic Iron(III)-Porphyrins

PROIETTI SILVESTRI, ILARIA;CELLESI, FRANCESCO
2015-01-01

Abstract

Commercially available hydrophobic porphyrins are investigated as an environmentally friendly catalytic system for iron-mediated atom transfer radical polymerization (ATRP) of poly(ethylene glycol) monomethyl ether methacrylate (PEGMA). Polymerizations in organic solvent are optimized using activators generated by electron transfer (AGET ATRP), based on iron(III)-porphyrin complexes, and tin(II) 2-ethyl hexanoate or ascorbic acid as a reducing agent. Copper-free PPEGMA macromolecules are obtained with high conversion, controlled molecular weight, and polydispersity index compared with standard copper-based ATRP. The facile preparation and availability of the catalyst, together with its expected low toxicity, represent clear advantages for the synthesis of PPEGMA-based materials for biomedical use.
2015
iron ATRP; poly[poly(ethylene glycol) methyl ether methacrylate]; porphyrin; Materials Chemistry2506 Metals and Alloys; Polymers and Plastics; Organic Chemistry; Physical and Theoretical Chemistry; Condensed Matter Physics
File in questo prodotto:
File Dimensione Formato  
Silvestri_et_al-2015-Macromolecular_Chemistry_and_Physics.pdf

Accesso riservato

Descrizione: Articolo
: Publisher’s version
Dimensione 655.87 kB
Formato Adobe PDF
655.87 kB Adobe PDF   Visualizza/Apri
AGET ATRP of Poly_11311-983894_Cellesi.pdf

accesso aperto

: Post-Print (DRAFT o Author’s Accepted Manuscript-AAM)
Dimensione 753.8 kB
Formato Adobe PDF
753.8 kB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11311/983894
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 10
  • ???jsp.display-item.citation.isi??? 10
social impact