The present invention is directed to sulfated oligosaccharides having 4, 5 or 6 saccharidic units and wherein a glycosidic bond between two saccharide units is substituted by a C-C bond, and wherein the sulfation degree expressed as percentage of OH groups substituted by a OSO 3 - group is comprised between 50 and 100 %. The sulfated oligosaccharides according to the invention are useful as a drug, in particular in the treatment of angiogenesis, metastasis, and inflammation.
MIMETICS OF SULFATED OLIGOSACCHARIDES
VISMARA, ELENA;
2009-01-01
Abstract
The present invention is directed to sulfated oligosaccharides having 4, 5 or 6 saccharidic units and wherein a glycosidic bond between two saccharide units is substituted by a C-C bond, and wherein the sulfation degree expressed as percentage of OH groups substituted by a OSO 3 - group is comprised between 50 and 100 %. The sulfated oligosaccharides according to the invention are useful as a drug, in particular in the treatment of angiogenesis, metastasis, and inflammation.File in questo prodotto:
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